Dr. Velculescu is Co-Director of Cancer Biology and Professor of Oncology and Pathology at the Johns Hopkins Kimmel Cancer Center, and is a co-founder of Personal Genome Diagnostics. Dr. Velculescu has made a number of important advances in genomics and cancer research, including the first sequence analysis of the coding genome in human cancers, which led to the identification of key genes and pathways dysregulated in tumorigenesis. He developed SAGE (serial analysis of gene expression) and coined the word “transcriptome” to describe the comprehensive gene expression. More recently, his group has focused on non-invasive liquid biopsies approaches for early tumor detection and monitoring. These discoveries have created new opportunities for precision diagnostics and personalized medicine in cancer.