Lung cancer is a significant global health burden, with diverse clinical outcomes and treatment responses. Understanding lung cancer in the context of different demographics and exposures is vital for tailored treatments. Dr. Pich’s project aims to integrate multiomics data from thousands of lung cancer patients across different countries to better characterize cancer evolution, with a focus on the interplay between tumor cells and the tumor microenvironment.
published research
Pich O, Ward S, Rowan A, Naceur-Lombardelli C, Shutkever O, Martinez-Ruiz C, Harries S, Hessey S, Naidu B, Brenton JD, Le Quesne J, Thomas A, Richards C, Krebs MG, Turajlic S, Jogai S, Zaccaria S, Moore D, Hiley CT; PEACE Consortium; Swanton C, Jamal-Hanjani M, McGranahan N. Somatic evolution following cancer treatment in normal tissue. Nature. 2025.