Our Portfolio

Featured Projects

The Adaptive and Innate Immune Responses to Inherited TP53 Breast Cancers in Li-Fraumeni Patients

ASPIRE Award (2021-Present)

Arnold Levine, PhD (Principal) Institute for Advanced Study; Mark Davis, PhD, Stanford University; David Malkin, MD, Hospital for Sick Kids; Raymond Kim, MD PhD, Princess Margaret Hospital; Judy Garber, MD, and Junne Kamihara, MD PhD, Dana Farber Cancer Institute; Joshua Schiffman, MD, Huntsman Cancer Institute; Mark Robson, MD, and Michael Walsh, MD, Memorial Sloan Kettering Cancer Center

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Leveraging oncRNAs to Derive Blood-Accessible QR Codes for Human Cancers

ASPIRE Award (2021-Present)

Hani Goodarzi, PhD, University of California, San Francisco

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Deep Neural Network Prediction of Relapse in Pediatric Acute Leukemia

ASPIRE Award, Phase II (2021-Present)

Kara Davis, DO, Stanford University

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Identifying Genes Uniquely Contributing to ICI-induced Immune Related Adverse Events

ASPIRE Award, Phase II (2021-Present)

David Serreze, PhD (Principal) and Nadia Rosenthal, PhD, FMedSci, (Co-Principal), The Jackson Laboratory

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Investigating the Essential Roles of Kelch-like Family Member KLHL11 in the Pathogenesis of Anaplastic Large Cell Lymphoma and in Normal T cells

IN PARTNERSHIP WITH GABRIELLE'S ANGEL FOUNDATION FOR CANCER RESEARCH (2021-PRESENT)

Yibin Yang, PhD, Fox Chase Cancer Center

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Dissecting the Role of the Unfolded Protein Response in Type 1 CALR-mutated Myelofibrosis

IN PARTNERSHIP WITH GABRIELLE'S ANGEL FOUNDATION FOR CANCER RESEARCH (2021-PRESENT)

Shannon Elf, PhD, University of Chicago

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Expanding Upon Induced Proximity-Based Therapeutic Modalities

Momentum Fellow (2021-Present)

James Papatzimas, PhD, University of California, Berkeley

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Roles of SIX1-GATA1-DACH1 Interactions in Acute Myeloid Leukemia

Momentum Fellow (2021-Present)

Minjung Kim, PhD, The University of Maryland

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Multi-antigen Specific T cells post-Hematopoietic Stem Cell Transplant to Enhance anti-Leukemia and anti-Viral Immunity in vivo

Momentum Fellow (2021-Present)

Hannah Kinoshita, MD, Children's National Hospital

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Leukemogenic Potential of Human Hematopoietic Stem Cells of Neonatal versus Adult Origin

Momentum Fellow (2021-Present)

Christian Marinaccio, PhD, Dana-Farber Cancer Institute

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Targeting the ART1-P2X7R-CD38 Axis for Cancer Immunotherapy

ASPIRE AWARD (2021-PRESENT)

Brendon Stiles, MD, Albert Einstein College of Medicine and Montefiore Medical Center

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Identification of a Novel Endogenous Small Molecule Suppressor of Innate Immunity

ASPIRE AWARD (2021-PRESENT)

Matthew Meyerson, MD, PhD, Broad Institute and Dana-Farber Cancer Institute

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Vaccine-boosted CAR T Cell Therapy as a Platform to Define Mechanisms Underlying Antigen Spreading during Immunotherapy

ASPIRE AWARD (2021-PRESENT)

Darrell Irvine, PhD, Massachusetts Institute of Technology

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Chemical Probe Discovery for Ligases that Govern MYC Post-Translational Stability

ASPIRE AWARD (2021-PRESENT)

Angela Koehler, PhD, Massachusetts Institute of Technology

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Characterization of a Novel Endothelial Network in Normal and Cancerous Tissues

ASPIRE AWARD (2021-PRESENT)

Jessica Blackburn, PhD, University of Kentucky

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Using glycan-targeting drugs to block prostate cancer bone metastasis

IN PARTNERSHIP WITH PROSTATE CANCER RESEARCH (2021-PRESENT)

Jennifer Munkley, PhD, Newcastle University

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