Optimizing MAPK Inhibitor Therapy for Pancreatic Cancer ASPIRE Award (2020-Present) Kevin Haigis, PhD (Principal) and Andrew Aguirre, MD, PhD, Dana-Farber Cancer Institute; Forest White, PhD, Massachusetts Institute of Technology Read More
Chromosomal Rearrangements and Their Associated Neo-Antigens as Predictors of Response and Survival to PD-1 Inhibition in Mesothelioma ASPIRE Award (2020-Present) Aaron Mansfield, MD, Mayo Clinic Read More
Disabling ER Stress Sensors to Unlock Adaptive Immunity Against Cancer ASPIRE AWARD (2018-2019; 2020-PRESENT) Juan Cubillos-Ruiz, PhD, Weill Cornell Medicine Read More
Overcoming BRAF/MEK Inhibition Resistance in Anaplastic Thyroid Carcinoma ASPIRE Award (2020-Present) Jennifer Wang, MD (Principal); Mark Zafereo, MD; and Wenyi Wang, PhD, MD Anderson Cancer Center Read More
Elucidating the Mechanism of Menin-MLL Interaction Inhibition in NPM1c Mutated Acute Myeloid Leukemia Momentum Fellow (2020-Present) Hannah Uckelmann, PhD, Dana-Farber Cancer Institute Read More
CBP/p300 Inhibitors for Genetically Defined Leukemias Drug Discovery Partnership (2020-Present) Philip Jones, PhD, MD Anderson Cancer Center Read More
Cysteine-Modification Screening to Identify Functional and Druggable Sites in Cancer Dependencies Damon Runyon - Mark Foundation Postdoctoral Fellow (2020-Present) Haoxin Li, PhD, The Scripps Research Institute Read More
Uncovering the Mystery of Metastatic Dormancy in Breast Cancer: An Unprecedented View ASPIRE Award (2020-Present) Alana Welm, PhD, University of Utah Read More
Targeting Leukemia Stem Cells by Disrupting Translational Fidelity IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT) Robert Signer, PhD, University of California San Diego Read More
Loss of the Non-Canonical BAF Complex as a Driver and Therapeutic Target in SF3B1-Mutant MDS and Leukemia IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT) Robert Bradley, PhD, Fred Hutchinson Cancer Research Center Read More
Clonal Evolution of Pre-Leukemic Hematopoietic Stem Cells in Human Myeloid Malignancies IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT) Ravi Majeti, MD, PhD, Stanford University School of Medicine Read More
Development and Application of a Pan-Cancer Diagnostic Test for Early Detection of Cancer Momentum Fellow (2020-Present) Dimitrios Mathios, MD, Johns Hopkins University School of Medicine Read More
Mechanisms of Tumor-Initiation in B-Lymphoid Malignancies IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT) Markus Müschen, MD, PhD, City of Hope Read More
Characterizing a Novel RasGRP1-mTOR Pathway in Immune and Cancer Cells Momentum Fellow (2020-Present) Kriti Bahl, PhD, University of California, San Francisco Read More
In Vivo Generation of Chimeric Antigen Receptor Cells to Treat Hemopoietic Malignancies IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT) Ron Levy, MD, Stanford University School of Medicine Read More
