Our Portfolio


Featured Projects

Molecular Mechanisms of Tumor Progression and Plasticity in Bladder Cancer

Endeavor Award (2020-Present)

Cory Abate-Shen, PhD, and Michael Shen, PhD, Columbia University - Principal Investigators

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Understand and Eliminate Metastatic Cancers

Endeavor Award (2020-Present)

Andrei Goga, MD, PhD; Eric Collisson, MD; Jay Debnath, MD, PhD; Sarah Knox, PhD; Jeroen Roose, PhD; and Valerie Weaver, PhD, University of California, San Francisco - Principal Investigators

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Host Response to Cancer

Endeavor Award (2020-Present)

Tobias Janowitz, MD, PhD and Semir Beyaz, PhD, Cold Spring Harbor Laboratory - Principal Investigators

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Evolution of Megakaryocyte Abnormalities in the Progression of Primary Myelofibrosis

The Mark Foundation for Cancer Research-Leukemia & Lymphoma Society Fellow (2021-Present)

Johanna Melo-Cardenas, PhD, St. Jude Children’s Research Hospital

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Cell Morphological Modulation of Oncogenic RAS Signaling

Damon Runyon - Mark Foundation Postdoctoral Fellow (2021-Present)

Gabriel Muhire Gihana, PhD, University of Texas Southwestern Medical Center

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Deciphering Immune Cell Heterogeneity and Transcriptomic Changes Associated with CRS Development and Severity in CAR-T Cell Treated Patients

The Mark Foundation for Cancer Research-Leukemia & Lymphoma Society Fellow (2021-Present)

Sylvain Simon, PhD, Fred Hutchinson Cancer Research Center

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Evaluating a Novel Collaboration Between NOTCH1 and MLL1 for Improved Targeted Treatments in T-ALL

The Mark Foundation for Cancer Research-Leukemia & Lymphoma Society Fellow (2021-Present)

Therese Vu, PhD, University of Colorado Denver

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Characterize the Role of Non-Vesicular Cholesterol Transport in CD8+ T Cell Function

Damon Runyon - Mark Foundation Postdoctoral Fellow (2021-Present)

Yajing Gao, PhD, University of California, Los Angeles

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Induced Proximity for Destabilization of Core Regulatory Factors in Alveolar Rhabdomyosarcoma

ASPIRE Award (2020-Present)

Benjamin Stanton, PhD (Principal), Nationwide Children's Hospital and Jun Qi, PhD, Dana-Farber Cancer Institute

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Evoking Immune Response Using Phosphorylation-Inducing Chimeric Small Molecules

ASPIRE Award (2020-Present)

Amit Choudhary, PhD, Harvard Medical School

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Evolutionary Distant DCC Populations Cooperate to Shape Lung Immune Niches for Dormancy and Reactivation

ASPIRE Award (2020-Present)

Julio Aguirre-Ghiso, PhD (Principal), Maria Soledad Sosa, PhD, and Brian Brown, PhD, Icahn School of Medicine at Mount Sinai

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New Molecular Glues to Target the RAS Pathway in Cancer

ASPIRE Award (2020-Present)

Arvin Dar, PhD, Icahn School of Medicine at Mount Sinai

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Development of a Brachyury Degrader

Drug Discovery Partnership (2020-Present)

Craig Crews, PhD, Yale University

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