Dr. Lahvic is investigating how neighboring normal cells will try to impede the growth of cancer cells, and how a tumor escapes these controls. Dr. Lahvic aims to understand the genetic predispositions to cancer and find clues to a new way of preventing and treating cancer: activation of normal cells to directly fight a nearby tumor. While this work could hold relevance for all carcinomas, she is focusing on Ras mutations, which are especially common in pancreatic and colon cancers.
Content courtesy of Damon Runyon Cancer Research Foundation
Lahvic JL, Hariharan IK. Harnessing epithelial homeostatic mechanisms to fight cancer. Mol Biol Cell. 2019.