Pancreatic cancer alters the body long before diagnosis, including shifting how tissues use and store iron. This project will investigate how early tumors reprogram iron balance and metabolism across the body, revealing the earliest biological events in pancreatic cancer development.
Dr. Christine Chio is an Assistant Professor of Genetics and Development at Columbia University Irving Medical Center and a member of the Herbert Irving Comprehensive Cancer Center. She received her PhD in Medical Biophysics from the University of Toronto and completed postdoctoral training at Cold Spring Harbor Laboratory. Dr. Chio’s research focuses on how redox-regulated metabolic pathways shape pancreatic cancer and influence systemic physiology. Her laboratory seeks to define the earliest biological events in pancreatic cancer and uncover metabolic vulnerabilities driven by redox signaling.