Natural torpor is an evolved strategy that animals use to conserve energy and survive harsh winter conditions. This project aims to define mechanisms by which synthetic torpor (torpor induced by neuromodulation) selectively stresses cancer cells to uncover novel targets for anti-cancer therapy.
Dr. Borniger is an assistant professor at Cold Spring Harbor Laboratory with appointments in the neuroscience division and cancer center. His laboratory is focused on characterizing and manipulating cancer-nervous system interactions across multiple spatiotemporal scales. Specifically, he is interested in how the nervous system detects and integrates information about cancer in the body, and how this information influences neuronal output pathways to drive changes in behavior and physiology.