Dr. Mardis is Co-Executive Director of the Institute for Genomic Medicine at Nationwide Children’s Hospital, and holds the Nationwide Foundation Endowed Chair in Genomic Medicine. She also teaches as a Professor of Pediatrics at the Ohio State University College of Medicine. Dr. Mardis served as President of the American Association of Cancer Research (AACR) from 2019-2020. Dr. Mardis’s group was one of the first to use next-generation sequencing to compare a cancer patient’s tumor DNA with normal tissue DNA to help identify mutations driving cancer growth. Her research interests focus on the application of next-generation sequencing to characterize cancer genomes and transcriptomes, and to support therapeutic decision-making. Her translational research efforts devise sequencing-based diagnostics, decision-support tools and databases, and the use of genomics to design personalized cancer vaccines.