Our Portfolio

New This Month – Projects Funded in Partnership with LLS and PAFG

Loss of the Non-Canonical BAF Complex as a Driver and Therapeutic Target in SF3B1-Mutant MDS and Leukemia

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Robert Bradley, PhD, Fred Hutchinson Cancer Research Center

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Targeting Leukemia Stem Cells by Disrupting Translational Fidelity

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Robert Signer, PhD, University of California San Diego

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Clonal Evolution of Pre-Leukemic Hematopoietic Stem Cells in Human Myeloid Malignancies

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Ravi Majeti, MD, PhD, Stanford University School of Medicine

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Mechanisms of Tumor-Initiation in B-Lymphoid Malignancies

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Markus Müschen, MD, PhD, City of Hope

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In Vivo Generation of Chimeric Antigen Receptor Cells to Treat Hemopoietic Malignancies

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Ron Levy, MD, Stanford University School of Medicine

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Detection and Targeting of Enzymatic Base Editing Deregulation in Leukemia Stem Cells

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Catriona Jamieson, MD, PhD, University of California San Diego

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The Cellular and Architectural Determinants of Immune Evasion and Their Impact on Response to Therapy in Classical Hodgkin Lymphoma

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Margaret A. Shipp, MD, Dana-Farber Cancer Institute/ Harvard Medical School

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T Cell Acute Lymphoblastic Leukemia Accumulation in the Central Nervous System

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Susan R. Schwab, PhD, New York University

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Rational Therapeutic Targeting of Oncogenic Immune Signaling States in Myeloid Malignancies

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Daniel T. Starczynowski, PhD, Cincinnati Children's Research Foundation

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Cysteine-Modification Screening to Identify Functional and Druggable Sites in Cancer Dependencies

Damon Runyon - Mark Foundation Postdoctoral Fellow (2020-Present)

Haoxin Li, PhD, The Scripps Research Institute

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Uncovering the Mystery of Metastatic Dormancy in Breast Cancer: An Unprecedented View

ASPIRE Award (2020-Present)

Alana Welm, PhD, University of Utah

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Elucidating the Mechanism of Menin-MLL Interaction Inhibition in NPM1c Mutated Acute Myeloid Leukemia

Momentum Fellow (2020-Present)

Hannah Uckelmann, PhD, Dana-Farber Cancer Institute

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Development and Application of a Pan-Cancer Diagnostic Test for Early Detection of Cancer

Momentum Fellow (2020-Present)

Dimitrios Mathios MD, Johns Hopkins University School of Medicine

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Characterizing a Novel RasGRP1-mTOR Pathway in Immune and Cancer Cells

Momentum Fellow (2020-Present)

Kriti Bahl, PhD, University of California, San Francisco

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Dissecting Tumor Intrinsic and Immune Drivers of Resistance to Therapy in Non-Small Cell Lung Cancer

Damon Runyon - Mark Foundation Physician-Scientist (2020-Present)

Natalie Vokes, MD, Dana-Farber Cancer Institute

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Statistical Approaches for Earlier Detection of Cancer

Momentum Fellow (2020-Present)

Stephen Cristiano, PhD, Johns Hopkins University School of Medicine

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Impact of Clonal Hematopoiesis on the Myeloid Gene Regulatory Networks that Modulate Cancer Evolution and Response to Therapy

Momentum Fellow (2020-Present)

Pablo Sánchez Vela, MD, Memorial Sloan Kettering Cancer Center

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A Liquid Biopsy Test for the Early Detection of High-Risk Colorectal Adenomas

ASPIRE Award (2020-Present)

Dan Landau, MD, PhD, Weill Cornell School of Medicine (Principal) and Claus Andersen, PhD, Aarhus University

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Blood-Based Cancer Screening for Lynch Syndrome Patients

ASPIRE AWARD (2020-Present)

Michael Berger, PhD, Memorial Sloan Kettering Cancer Center

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