Our Portfolio


Featured Projects

Chromosomal Rearrangements and Their Associated Neo-Antigens as Predictors of Response and Survival to PD-1 Inhibition in Mesothelioma

ASPIRE Award (2020-Present)

Aaron Mansfield, MD, Mayo Clinic

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Disabling ER Stress Sensors to Unlock Adaptive Immunity Against Cancer

ASPIRE AWARD (2018-2019; 2020-PRESENT)

Juan Cubillos-Ruiz, PhD, Weill Cornell Medicine

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Overcoming BRAF/MEK Inhibition Resistance in Anaplastic Thyroid Carcinoma

ASPIRE Award (2020-Present)

Jennifer Wang, MD (Principal); Mark Zafereo, MD; and Wenyi Wang, PhD, MD Anderson Cancer Center

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Elucidating the Mechanism of Menin-MLL Interaction Inhibition in NPM1c Mutated Acute Myeloid Leukemia

Momentum Fellow (2020-Present)

Hannah Uckelmann, PhD, Dana-Farber Cancer Institute

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CBP/p300 Inhibitors for Genetically Defined Leukemias

Drug Discovery Partnership (2020-Present)

Philip Jones, PhD, MD Anderson Cancer Center

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Cysteine-Modification Screening to Identify Functional and Druggable Sites in Cancer Dependencies

Damon Runyon - Mark Foundation Postdoctoral Fellow (2020-Present)

Haoxin Li, PhD, The Scripps Research Institute

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Uncovering the Mystery of Metastatic Dormancy in Breast Cancer: An Unprecedented View

ASPIRE Award (2020-Present)

Alana Welm, PhD, University of Utah

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Loss of the Non-Canonical BAF Complex as a Driver and Therapeutic Target in SF3B1-Mutant MDS and Leukemia

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Robert Bradley, PhD, Fred Hutchinson Cancer Research Center

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Targeting Leukemia Stem Cells by Disrupting Translational Fidelity

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Robert Signer, PhD, University of California San Diego

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Clonal Evolution of Pre-Leukemic Hematopoietic Stem Cells in Human Myeloid Malignancies

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Ravi Majeti, MD, PhD, Stanford University School of Medicine

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Development and Application of a Pan-Cancer Diagnostic Test for Early Detection of Cancer

Momentum Fellow (2020-Present)

Dimitrios Mathios, MD, Johns Hopkins University School of Medicine

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Mechanisms of Tumor-Initiation in B-Lymphoid Malignancies

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Markus Müschen, MD, PhD, City of Hope

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Characterizing a Novel RasGRP1-mTOR Pathway in Immune and Cancer Cells

Momentum Fellow (2020-Present)

Kriti Bahl, PhD, University of California, San Francisco

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In Vivo Generation of Chimeric Antigen Receptor Cells to Treat Hemopoietic Malignancies

IN PARTNERSHIP WITH LEUKEMIA & LYMPHOMA SOCIETY AND THE PAUL G. ALLEN FRONTIERS GROUP (2020-PRESENT)

Ron Levy, MD, Stanford University School of Medicine

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