Dr. Kohlgruber is identifying neoantigens from breast cancer that can be recognized by CD8+ T cells of the immune system.
published research
Kohlgruber AC, Dezfulian MH, Sie BM, Wang CI, Kula T, Laserson U, Larman HB, Elledge SJ. High-throughput discovery of MHC class I- and II-restricted T cell epitopes using synthetic cellular circuits. Nat Biotechnol. 2024.