Systems Analysis of In Vivo Tumor and Stromal Cell Metabolism in Pancreatic Ductal Adenocarcinoma

Damon Runyon - Mark Foundation Postdoctoral Fellow (2019-Present)

Caroline Bartman, PhD, Princeton University

Dr. Bartman studies the unique nutritional requirements of cancer cells compared to healthy tissues. Dr. Bartman will use mass spectrometry measurements of labeled nutrients and computational modeling to quantify metabolic fluctuations in both pancreatic cancer cells and healthy organs in mice. Since altered metabolism is a hallmark of cancer cells, systematically mapping these metabolic changes may guide drug development to rationally target cancer while sparing healthy cells.

Content courtesy of Damon Runyon Cancer Research Foundation