Genomic and Epidemiological Characterization of Early-Age Onset Colorectal Cancers

Dr. Oliveira dos Santos’ project objective is to identify mutational signatures and characterize the microbiome profile of early-age onset colorectal cancer tumor samples and combine the findings with patient’s epidemiological information (demographics, lifestyle and exposure), to elucidate probable causes and biological mechanisms related to the onset of these tumors and to apply this knowledge to cancer prevention and treatment management.