IMMUNESCAPE – Dissecting the Impact of Clonal Evolutionary Dynamics on Tumor Immunogenicity


IN PARTNERSHIP WITH THE EUROPEAN ASSOCIATION FOR CANCER RESEARCH AND THE PEZCOLLER FOUNDATION (2023-PRESENT)

Isidro Cortés-Ciriano, PhD, EMBL-European Bioinformatics Institute

Isidro Cortés-Ciriano, PhD

Dr. Isidro Cortés-Ciriano has been selected as the recipient of the inaugural EACR-Mark Foundation-Pezcoller Foundation Rising Star Award.

Dr. Cortés-Ciriano commented “I am truly honored to receive this prestigious award, and deeply thankful to the EACR, the Mark Foundation, and the Pezcoller Foundation for supporting the research vision of my laboratory. We are most excited to continue our work focused on understanding how the interplay between genetic diversity and immunosurveillance shapes the evolution and immunogenicity of human cancers. We hope that by decoding the molecular mechanisms whereby cancer cells manage to escape the attack of the immune system, we will contribute to the design of novel cancer immunotherapies.

“More broadly, this project will also help us understand how the immune system responds to the myriad of somatic mutations accumulated in our bodies as we age, which might shed light on the relationship between somatic evolution, immune evasion, and malignant transformation.”

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