Understanding the Intestinal Stem Cell Compartment in Health and Disease


Momentum Fellow (2018-2020)

Dr. Depeille is analyzing how intestinal homeostasis is maintained with a high turnover and consistent draw of the stem cell niche, which will provide insight into initiation of colorectal cancer.

PUBLISHED RESEARCH

Gbenedio OM, Bonnans C, Grun D, Wang CY, Hatch AJ, Mahoney MR, Barras D, Matli M, Miao Y, Garcia KC, Tejpar S, Delorenzi M, Venook AP, Nixon AB, Warren RS, Roose JP, Depeille P. RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer. JCI Insight. 2019.

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