Investigating the Mechanisms of Cotargeting PD1 and LAG3 for Immunotherapy


Momentum Fellow (2018-Present)

Shin Foong Ngiow, PhD, University of Pennsylvania School of Medicine

Dr. Ngiow is investigating how different proteins can be simultaneously targeted to make immunotherapy more effective.

PUBLISHED RESEARCH

Beltra JC, Manne S, Abdel-Hakeem MS, Kurachi M, Giles JR, Chen Z, Casella V, Ngiow SF, Khan O, Huang YJ, Yan P, Nzingha K, Xu W, Amaravadi RK, Xu X, Karakousis GC, Mitchell TC, Schuchter LM, Huang AC, Wherry EJ. Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms. Immunity. 2020.

Ngiow SF, Young A. Re-education of the Tumor Microenvironment With Targeted Therapies and Immunotherapies. Front Immunol. 2020.

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