Investigating the Mechanisms of Cotargeting PD1 and LAG3 for Immunotherapy


Momentum Fellow (2018-Present)

Dr. Ngiow is investigating how different proteins can be simultaneously targeted to make immunotherapy more effective.

PUBLISHED RESEARCH

Beltra JC, Manne S, Abdel-Hakeem MS, Kurachi M, Giles JR, Chen Z, Casella V, Ngiow SF, Khan O, Huang YJ, Yan P, Nzingha K, Xu W, Amaravadi RK, Xu X, Karakousis GC, Mitchell TC, Schuchter LM, Huang AC, Wherry EJ. Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms. Immunity. 2020.

BACK TO OUR PORTFOLIO