Structure-Guided Drug Discovery for Brachyury Inhibitors

Therapeutic Innovation Award, in partnership with Chordoma Foundation (2018-Present)

Opher Gileadi, PhD, University of Oxford; David Drewry, PhD, University of North Carolina; Charles Lin, PhD, Baylor College of Medicine

A cutting-edge structural biology approach to identify candidate small molecules that inhibit the function of the transcription factor brachyury