The Mark Foundation is proud to support groundbreaking cancer research leading to several recent high-profile publications. These studies, ranging from the bench to the bedside, are funded by Mark Foundation grant programs including the ASPIRE Award, Drug Discovery Award, Emerging Leader Award, Endeavor Award, and Momentum Fellowship, as well as through partnerships with other high-impact cancer research organizations. Scroll down to learn more.
- In Nature Communication, MAPS: pathologist-level cell type annotation from tissue images through machine learning
- From Blood Cancer Discoveries Grant Awardee Margaret Shipp (in partnership with The Leukemia & Lymphoma Society and The Paul G. Allen Frontiers Group)
- In Cancer Discovery, Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms
- From Emerging Leader Awardee Dan Landau
- In Nature Cancer, Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation
- From Endeavor Awardee Tobias Janowitz
- In Frontiers in Immunology, Quantitative multiplex immunohistochemistry reveals inter-patient lymphovascular and immune heterogeneity in primary cutaneous melanoma
- From Emerging Leader Awardee Amanda Lund
- In Nature, Naturally occurring T cell mutations enhance engineered T cell therapies
- From Emerging Leader Awardee Jaehyuk Choi
- In Angewandte Chemie International Edition, Development of a Covalent Small Molecule Downmodulator for the Transcription Factor Brachyury
- From Drug Discovery Awardee Craig Crews
- In Cancer Cell, Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment
- From ASPIRE Awardee Mikala Egeblad
- In Nature Genetics, Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns
- From the SpecifiCancer team, in partnership with Cancer Research UK
- In Nature Medicine, Neoadjuvant nivolumab or nivolumab plus LAG-3 inhibitor relatlimab in resectable esophageal/gastroesophageal junction cancer: a phase Ib trial and ctDNA analyses
- From Valsamo Anagnostou, in partnership with Cancer Research Institute
- In Nature, Proteome-scale discovery of protein degradation and stabilization effectors
- From ASPIRE Awardee Mikko Taipale
- In Frontiers in Immunology, Development of a customizable mouse backbone spectral flow cytometry panel to delineate immune cell populations in normal and tumor tissues
- From Momentum Fellow Inés Fernández Maestre
- In Cancer Cell, Research autopsy programmes in oncology: shared experience from 14 centres across the world
- From ASPIRE Awardee Alana Welm